Preclinical R&D Services
Large animal models
Clinical R&D Services
Investigator Initiated Trials
Regulatory, ethics committee
Preclinical r&d services
Our innovative R&D solutions (InnoRD™) reduce the time of your development as we develop the best preclinical models for your needs.
Complex animal models of cardiovascular (e.g. infarction, heart failure, stroke) and metabolic diseases (e.g. diabetes, hyperlipidemia, atherosclerosis, obesity, aging) for proof-of-concept studies.
We design custom models for your needs.
Special risk sharing opportunities available.
: Cardiovascular Technology platform for preclinical R&D is under continuous development.
: Metabolic Technology platform for preclinical contract research is under continuous development.
Large Animal Models
: We provide large animal models for different indication.
EXAMPLES OF OUR RESEARCH SERVICES IN COMPLEX IN VIVO AND EX VIVO MODELS OF VARIOUS DISEASES, ASK FOR FURTHER DETAILS:
Testing cardioprotective compounds on acute and chronic coronary occlusion-induced myocardial ischemia/reperfusion, myocardial infarction, preconditioning, and postconditioning.
Testing compounds for heart failure induced by chronic coronary occlusion-induced infarction, isoproterenol, or cardiotoxic agents such as doxorubicin.
Testing cardioprotective compounds in organ storage models.
Testing vascular functions in hyperlipidemia/atherosclerosis and nitrate-tolerance models.
Evaluation of antidiabetic compounds in type 1 and type 2 diabetic models (STZ, Goto-Kakizaki, Zucker Diabetic Fatty, etc).
Evaluation of compounds acting on the nitric oxide-cGMP system and peroxynitrite formation, e.g. peroxynitrite scavengers.
Testing antiplatelet compounds in platelet aggregation systems.
Testing antioxidant agents in cardiovascular and metabolic disease models.
Evaluation of cardiac heat-shock protein (HSP) inducers. Evaluation of matrix metalloproteinase (MMP) inhibitors.
For further details on our innovative precilinical (nonclinical) services, please do not hesitate to contact us at