Isolated cardiomyocyte model for essential information on the cardiac electrophysiologic effects and safety of compounds.
Available species: rabbit, guinea pig, rat, dog.
QT prolongation with continuous action potential parameters, e.g. duration, amplitude, resting potential, etc.
Available species: rabbit, guinea pig, dog.
Different heart muscle preparations: papillary muscle, Purkinje-fiber, atrial muscle, etc.
Automated planar patch-clamp method on genetically modified mammalian cell lines for voltage- and ligand-gated ion channels as well as temperature-activated channels in gigaseal quality.
Wide range of ex vivo and in vivo cardiac electrophysiology models, e.g. chronic atrial fibrillation model, etc.