Schreckenberg R, Woitasky N, Itani N, Czech L, Ferdinandy P, Schulz R.
Cardiac side effects of RNA-based SARS-CoV-2 vaccines: Hidden cardiotoxic effects of mRNA-1273 and BNT162b2 on ventricular myocyte function and structure.
Br J Pharmacol. 2023 Oct 12.
Fodor E, Nagy RN, Nógrádi A, Toovey S, Kamal MA, Vadász P, Bencsik P, Görbe A, Ferdinandy P.
An Observational Study on the Pharmacokinetics of Oseltamivir in Lactating Influenza Patients.
Clin Pharmacol Ther. 2023 Nov 17.
Haj-Yehia E, Mincu RI, Korste S, Lampe L, Margraf SM, Michel L, Mahabadi AA, Ferdinandy P, Rassaf T, Totzeck M.
High neutrophil-to-lymphocyte ratio is associated with cancer therapy-related cardiovascular toxicity in high-risk cancer patients under immune checkpoint inhibitor therapy.
Clin Res Cardiol. 2023 Nov 13.
Ungvari Z, Tabák AG, Adany R, Purebl G, Kaposvári C, Fazekas-Pongor V, Csípő T, Szarvas Z, Horváth K, Mukli P, Balog P, Bodizs R, Ujma P, Stauder A, Belsky DW, Kovács I, Yabluchanskiy A, Maier AB, Moizs M, Östlin P, Yon Y, Varga P, Vokó Z, Papp M, Takács I, Vásárhelyi B, Torzsa P, Ferdinandy P, Csiszar A, Benyó Z, Szabó AJ, Dörnyei G, Kivimäki M, Kellermayer M, Merkely B.
The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging.
Geroscience. 2023 Dec 7. Epub ahead of print. PMID: 38060158.
Heger J, Partsch S, Harjung C, Varga ZV, Baranyai T, Weiß J, Kremer L, Locquet F, Leszek P, Ágg B, Benczik B, Ferdinandy P, Schulz R, Euler G.
YB-1 Is a Novel Target for the Inhibition of α-Adrenergic-Induced Hypertrophy.
Int J Mol Sci. 2023 Dec 28;25(1):401.
Gergely TG, Drobni ZD, Kallikourdis M, Zhu H, Meijers WC, Neilan TG, Rassaf T, Ferdinandy P, Varga ZV.
Immune checkpoints in cardiac physiology and pathology: therapeutic targets for heart failure.
Nat Rev Cardiol. 2024 Jan 26.
Tamargo J, Agewall S, Borghi C, Ceconi C, Cerbai E, Dan GA, Ferdinandy P, Grove EL, Rocca B, Magavern E, Sulzgruber P, Semb AG, Sossalla S, Niessner A, Kaski JC, Dobrev D.
New pharmacological agents and novel cardiovascular pharmacotherapy strategies in 2023.
Eur Heart J Cardiovasc Pharmacother. 2024 Feb 20:pvae013.
Papapetropoulos A, Topouzis S, Alexander SPH, Cortese-Krott M, Kendall DA, Martemyanov KA, Mauro C, Nagercoil N, Panettieri RA Jr, Patel HH, Schulz R, Stefanska B, Stephens GJ, Teixeira MM, Vergnolle N, Wang X, Ferdinandy P.
Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review.
Br J Pharmacol. 2024 Mar 22.
Sayour NV, Paál ÁM, Ameri P, Meijers WC, Minotti G, Andreadou I, Lombardo A, Camilli M, Drexel H, Grove EL, Dan GA, Ivanescu A, Semb AG, Savarese G, Dobrev D, Crea F, Kaski JC, de Boer RA, Ferdinandy P, Varga ZV.
Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence.
Eur Heart J. 2024 Mar 5.
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Cellular Alterations in Immune Checkpoint Inhibitor Therapy-Related Cardiac Dysfunction.
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Effects of Bempedoic Acid in Acute Myocardial Infarction in Rats: No Cardioprotection and No Hidden Cardiotoxicity.
Int J Mol Sci. 2023 Jan 13;24(2):1585.
Kucsera D, Tóth VE, Sayour NV, Kovács T, Gergely TG, Ruppert M, Radovits T, Fábián A, Kovács A, Merkely B, Ferdinandy P, Varga ZV.
IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH.
Sci Rep. 2023 Jan 7;13(1):356.
Sayour NV, Brenner GB, Makkos A, Kiss B, Kovácsházi C, Gergely TG, Aukrust SG, Tian H, Zenkl V, Gömöri K, Szabados T, Bencsik P, Heinen A, Schulz R, Baxter GF, Zuurbier CJ, Vokó Z, Ferdinandy P, Giricz Z.
Cardioprotective efficacy of limb remote ischemic preconditioning in rats: discrepancy between meta-analysis and a three-centre in vivo study.
Cardiovasc Res. 2023 Jun 13;119(6):1336-1351.
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Ferdinandy P, Andreadou I, Baxter GF, Bøtker HE, Davidson SM, Dobrev D, Gersh BJ, Heusch G, Lecour S, Ruiz-Meana M, Zuurbier CJ, Hausenloy DJ, Schulz R.
Interaction of Cardiovascular Nonmodifiable Risk Factors, Comorbidities and Comedications With Ischemia/Reperfusion Injury and Cardioprotection by Pharmacological Treatments and Ischemic Conditioning.
Pharmacol Rev. 2023 Jan;75(1):159-216.
Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Panettieri RA Jr, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P, Ahluwalia A.
Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology.
Br J Pharmacol. 2023 May;180(9):1191-1196.
Wang XW, Madeddu L, Spirohn K, Martini L, Fazzone A, Becchetti L, Wytock TP, Kovács IA, Balogh OM, Benczik B, Pétervári M, Ágg B, Ferdinandy P, Vulliard L, Menche J, Colonnese S, Petti M, Scarano G, Cuomo F, Hao T, Laval F, Willems L, Twizere JC, Vidal M, Calderwood MA, Petrillo E, Barabási AL, Silverman EK, Loscalzo J, Velardi P, Liu YY.
Assessment of community efforts to advance network-based prediction of protein-protein interactions.
Nat Commun. 2023 Mar 22;14(1):1582.
Heusch G, Bøtker HE, Ferdinandy P, Schulz R.
Primordial non-responsiveness: a neglected obstacle to cardioprotection.
Eur Heart J. 2023 May 14;44(19):1687-1689.
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Sex Difference in Cardioprotection against Acute Myocardial Infarction in MAO-B Knockout Mice In Vivo.
Int J Mol Sci. 2023 Mar 29;24(7):6443.
Panettieri RA Jr, Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P, Ahluwalia A.
BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure.
Br J Pharmacol. 2023 Jun;180(12):1537-1541.
Onódi Z, Szabó PL, Kucsera D, Pokreisz P, Dostal C, Hilber K, Oudit GY, Podesser BK, Ferdinandy P, Varga ZV, Kiss A.
Inflammasome Activity in the Skeletal Muscle and Heart of Rodent Models for Duchenne Muscular Dystrophy.
Int J Mol Sci. 2023 May 9;24(10):8497.
Tamargo J, Agewall S, Borghi C, Ceconi C, Cerbai E, Dan GA, Ferdinandy P, Grove EL, Rocca B, Sulzgruber P, Semb AG, Sossalla S, Niessner A, Kaski JC, Dobrev D.
New pharmacological agents and novel cardiovascular pharmacotherapy strategies in 2022.
Eur Heart J Cardiovasc Pharmacother. 2023 May 11;9(4):353-370.
Felici T, Skinner R, Ferdinandy P, Varga ZV, Lombardo A, Camilli M.
Editorial: Cardiovascular sequelae of chemotherapy and radiotherapy in cancer
survivors: current evidence and perspectives.
Front Cardiovasc Med. 2023 Jun 20;10:1230862.
Pálóczi J, Paál Á, Pigler J, Kiss B, Rhoden A, Varga ZV, Ferdinandy P, Eschenhagen T, Görbe A.
Organ-specific model of simulated ischemia/reperfusion and hyperglycemia based on engineered heart tissue.
Vascul Pharmacol. 2023 Oct:152:107208.
Barachini S, Ghelardoni S, Varga ZV, Mehanna RA, Montt-Guevara MM, Ferdinandy P, Madonna R.
Antineoplastic drugs inducing cardiac and vascular toxicity – An update.
Vascul Pharmacol. 2023 Sep 7;153:107223.
Ruppert M, Korkmaz-Icöz S, Benczik B, Ágg B, Nagy D, Bálint T, Sayour AA, Oláh A, Barta BA, Benke K, Ferdinandy P, Karck M, Merkely B, Radovits T, Szabó G.
Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats.
Sci Rep. 2023 Sep 26;13(1):16122.
Sayour NV, Tóth VÉ, Nagy RN, Vörös I, Gergely TG, Onódi Z, Nagy N, Bödör C, Váradi B, Ruppert M, Radovits T, Bleckwedel F, Zelarayán LC, Pacher P, Ágg B, Görbe A, Ferdinandy P, Varga ZV.
Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction.
Int J Mol Sci. 2023 Sep 7;24(18):13826.
Heusch G, Andreadou I, Bell R, Bertero E, Botker HE, Davidson SM, Downey J, Eaton P, Ferdinandy P, Gersh BJ, Giacca M, Hausenloy DJ, Ibanez B, Krieg T, Maack C, Schulz R, Sellke F, Shah AM, Thiele H, Yellon DM, Di Lisa F.
Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection.
Redox Biol. 2023 Nov:67:102894.
Sundaramurthi H, Tonelotto V, Wynne K, O’Connell F, O’Reilly E, Costa-Garcia M, Kovácsházi C, Kittel A, Marcone S, Blanco A, Pallinger E, Hambalkó S, Piulats Rodriguez JM, Ferdinandy P, O’Sullivan J, Matallanas D, Jensen LD, Giricz Z, Kennedy BN.
Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes.
Open Res Eur. 2023 Nov 13;3:88.
Hargita Hegyesi, Éva Pallinger, Szabina Mecsei, Balázs Hornyák, Csenger Kovácsházi, Gábor B Brenner, Zoltán Giricz, Krisztina Pálóczi, Ágnes Kittel, József Tóvári, Lilla Turiak, Delaram Khamari, Péter Ferdinandy, Edit I Buzás
Circulating cardiomyocyte-derived extracellular vesicles reflect cardiac injury during systemic inflammatory response syndrome in mice
Cell Mol Life Sci. 2022 Jan 20;79(2):84.
Jolanda van der Velden, Folkert W Asselbergs, Jeroen Bakkers, Sandor Batkai, Luc Bertrand, Connie R Bezzina, Ilze Bot, Bianca Brundel, Lucie Carrier, Steven Chamuleau, Michele Ciccarelli, Dana Dawson, Sean M Davidson, Andreas Dendorfer, Dirk J Duncker, Thomas Eschenhagen, Larissa Fabritz, Ines Falcão-Pires, Péter Ferdinandy, Mauro Giacca, Henrique Girao, Can Gollmann-Tepeköylü, Mariann Gyongyosi, Tomasz J Guzik, Nazha Hamdani, Stephane Heymans, Andres Hilfiker, Denise Hilfiker-Kleiner, Alfons G Hoekstra, Jean-Sébastien Hulot, Diederik W D Kuster, Linda W van Laake, Sandrine Lecour, Tim Leiner, Wolfgang A Linke, Joost Lumens, Esther Lutgens, Rosalinda Madonna, Lars Maegdefessel, Manuel Mayr, Peter van der Meer, Robert Passier, Filippo Perbellini, Cinzia Perrino, Maurizio Pesce, Silvia Priori, Carol Ann Remme, Bodo Rosenhahn, Ulrich Schotten, Rainer Schulz, Karin Sipido, Joost P G Sluijter, Frank van Steenbeek, Sabine Steffens, Cesare M Terracciano, Carlo Gabriele Tocchetti, Patricia Vlasman, Kak Khee Yeung, Serena Zacchigna, Dayenne Zwaagman, Thomas Thum
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart
Cardiovasc Res. 2022 Jan 6;cvab370.
Olivér M Balogh, Bettina Benczik, András Horváth, Mátyás Pétervári, Péter Csermely, Péter Ferdinandy, Bence Ágg
Efficient link prediction in the protein-protein interaction network using topological information in a generative adversarial network machine learning model
BMC Bioinformatics. 2022 Feb 19;23(1):78.
Ákos Nádasdi, György Sinkovits, Ilona Bobek, Botond Lakatos, Zsolt Förhécz, Zita Z Prohászka, Marienn Réti, Miklós Arató, Gellért Cseh, Tamás Masszi, Béla Merkely, Péter Ferdinandy, István Vályi-Nagy, Zoltán Prohászka, Gábor Firneisz
Decreased circulating dipeptidyl peptidase-4 enzyme activity is prognostic for severe outcomes in COVID-19 inpatients
Biomark Med. 2022 Feb 23.
Muhammad Aslam, Hafiza Idrees, Peter Ferdinandy, Zsuzsanna Helyes, Christian Hamm, Rainer Schulz
Somatostatin Primes Endothelial Cells for Agonist-Induced Hyperpermeability and Angiogenesis In Vitro
Int J Mol Sci. 2022 Mar 13;23(6):3098.
Péter Ferdinandy, Ákos Koller, Christian Weber, Johann Wojta, Johannes Waltenberger
Frontiers of CardioVascular Biomedicine 2022 Budapest is on in person! The excellent program proves that scientists won against Covid-19
Cardiovasc Res. 2022 Apr 19;cvac064.
Dóra Szabó, Zsolt Sárszegi, Beáta Polgár, Éva Sághy, Dóra Reglődi, Tünde Tóth, Zsófia Onódi, Przemyslaw Leszek, Zoltán V Varga, Zsuzsanna Helyes, Ágnes Kemény, Péter Ferdinandy, Andrea Tamás
PACAP-38 and PAC1 Receptor Alterations in Plasma and Cardiac Tissue Samples of Heart Failure Patients
Int J Mol Sci. 2022 Mar 28;23(7):3715.
Szilvia Kugler, Zsófia Onódi, Mihály Ruppert, Alex Ali Sayour, Attila Oláh, Kálmán Benke, Péter Ferdinandy, Béla Merkely, Tamás Radovits, Zoltán V Varga
Inflammasome activation in end-stage heart failure-associated atrial fibrillation
ESC Heart Fail. 2022 May 18.
Kamilla Gömöri, Melissa Herwig, Heidi Budde, Roua Hassoun, Nusratul Mostafi, Saltanat Zhazykbayeva, Marcel Sieme, Suvasini Modi, Tamara Szabados, Judit Pipis, Nikolett Farkas-Morvay, István Leprán, Gergely Ágoston, István Baczkó, Árpád Kovács, Andreas Mügge, Péter Ferdinandy, Anikó Görbe, Péter Bencsik, Nazha Hamdani
Ca2+/calmodulin-dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model
ESC Heart Fail. 2022 May 18.
Levon M Khachigian, Brian L Black, Péter Ferdinandy, Raffaele De Caterina, Rosalinda Madonna, Yong-Jian Geng
Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: Novel targets for therapy
Vascul Pharmacol. 2022 Jul 24;107091.
Imre Vörös, Zsófia Onódi, Viktória Éva Tóth, Tamás G Gergely, Éva Sághy, Anikó Görbe, Ágnes Kemény, Przemyslaw Leszek, Zsuzsanna Helyes, Péter Ferdinandy, Zoltán V Varga
Saxagliptin Cardiotoxicity in Chronic Heart Failure: The Role of DPP4 in the Regulation of Neuropeptide Tone
Biomedicines. 2022 Jul 1;10(7):1573.
Mariann Gyöngyösi, Pilar Alcaide, Folkert W Asselbergs, Bianca J J M Brundel, Giovanni G Camici, Paula da Costa Martins, Péter Ferdinandy, Marianna Fontana, Henrique Girao, Massimiliano Gnecchi, Can Gollmann-Tepeköylü, Petra Kleinbongard, Thomas Krieg, Rosalinda Madonna, Melanie Paillard, Antonis Pantazis Cinzia Perrino, Maurizio Pesce, Gabriele G Schiattarella, Joost P G Sluijter, Sabine Steffens, Carsten Tschöpe, Sophie Van Linthout, Sean M Davidson
Long COVID and the cardiovascular system – elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: A joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial & Pericardial Diseases
Cardiovasc Res. 2022 Jul 25;cvac115.
Rolf Schreckenberg, Annemarie Wolf, Tamara Szabados, Kamilla Gömöri, István Adorján Szabó, Gergely Ágoston, Gábor Brenner, Péter Bencsik, Péter Ferdinandy, Rainer Schulz, Klaus-Dieter Schlüter
Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Deletion but Not Inhibition of Extracellular PCSK9 Reduces Infarct Sizes Ex Vivo but Not In Vivo
Int J Mol Sci. 2022 Jun 10;23(12):6512.
Béla Merkely, László Gellér, Endre Zima, István Osztheimer, Levente Molnár, Csaba Földesi, Gábor Duray, Jerzy K Wranicz, Marianna Németh, Kinga Goscinska-Bis, Robert Hatala, László Sághy, Boglárka Veres, Walter Richard Schwertner, Alexandra Fábián, Eszter Fodor, Ilan Goldenberg, Valentina Kutyifa, Attila Kovács, Annamária Kosztin
Baseline clinical characteristics of heart failure patients with reduced ejection fraction enrolled in the BUDAPEST-CRT Upgrade trial
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Mátyás Pétervári, Bettina Benczik, Olivér M Balogh, Balázs Petrovich, Bence Ágg, Péter Ferdinandy
Network Analysis for Signal Detection in Spontaneous Adverse Event Reporting Database: Application of Network Weighting Normalization to Characterize Cardiovascular Drug Safety
Drug Saf. 2022 Nov;45(11):1423-1438.
Bennet Y Weber, Gábor B Brenner, Bernadett Kiss, Tamás G Gergely, Nabil V Sayour, Huimin Tian, András Makkos, Anikó Görbe, Péter Ferdinandy, Zoltán Giricz
Rosiglitazone Does Not Show Major Hidden Cardiotoxicity in Models of Ischemia/Reperfusion but Abolishes Ischemic Preconditioning-Induced Antiarrhythmic Effects in Rats In Vivo
Pharmaceuticals (Basel). 2022 Aug 26;15(9):1055.
Timea Aczél, Bettina Benczik, Bence Ágg, Tamás Körtési, Péter Urbán, Witold Bauer, Attila Gyenesei, Bernadett Tuka, János Tajti, Péter Ferdinandy, László Vécsei, Kata Bölcskei, József Kun, Zsuzsanna Helyes
Disease- and headache-specific microRNA signatures and their predicted mRNA targets in peripheral blood mononuclear cells in migraineurs: role of inflammatory signalling and oxidative stress
J Headache Pain. 2022 Sep 2;23(1):113.
Gömöri K, Herwig M, Hassoun R, Budde H, Mostafi N, Delalat S, Modi S, Begovic M, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N.
Altered Cellular Protein Quality Control System Modulates Cardiomyocyte Function in Volume Overload-Induced Hypertrophy.
Antioxidants (Basel). 2022 Nov 8;11(11):2210.
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Molecular characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals IL-17A as a driver of cardiac dysfunction after anti-PD-1 treatment.
Br J Pharmacol. 2022 Nov 10.
Efentakis P, Andreadou I, Iliodromitis KE, Triposkiadis F, Ferdinandy P, Schulz R, Iliodromitis EK.
Myocardial Protection and Current Cancer Therapy: Two Opposite Targets with Inevitable Cost.
Int J Mol Sci. 2022 Nov 15;23(22):14121.
Onódi Z, Koch S, Rubinstein J, Ferdinandy P, Varga ZV.
Drug repurposing for cardiovascular diseases: new targets and indications for probenecid.
Br J Pharmacol. 2022 Dec 9. doi: 10.1111/bph.16001. Epub ahead of print. PMID: 36484549.
András Makkos, Bence Ágg, Zoltán V Varga, Zoltán Giricz, Mariann Gyöngyösi, Dominika Lukovic, Rainer Schulz, Monika Barteková, Anikó Görbe, Péter Ferdinandy
Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs
Int J Mol Sci. 2021 Sep 2;22(17):9539.
Marek Jelemenský, Csenger Kovácsházi, Kristína Ferenczyová, Monika Hofbauerová, Bernadett Kiss, Éva Pállinger, Ágnes Kittel, Viktor Nabil Sayour, Anikó Görbe, Csilla Pelyhe, Szabolcs Hambalkó, Lucia Kindernay, Miroslav Barančík, Péter Ferdinandy, Monika Barteková, Zoltán Giricz
Helium Conditioning Increases Cardiac Fibroblast Migration Which Effect Is Not Propagated via Soluble Factors or Extracellular Vesicles
Int J Mol Sci. 2021 Sep 29;22(19):10504.
Imre Vörös, Éva Sághy, Krisztina Pohóczky, András Makkos, Zsófia Onódi, Gábor B Brenner, Tamás Baranyai, Bence Ágg, Barnabás Váradi, Ágnes Kemény, Przemyslaw Leszek, Anikó Görbe, Zoltán V Varga, Zoltán Giricz, Rainer Schulz, Zsuzsanna Helyes, Péter Ferdinandy
Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection
Front Pharmacol. 2021 Nov 5;12:663655.
Zsófia Onódi, Tamás Visnovitz, Bernadett Kiss, Szabolcs Hambalkó, Anna Koncz, Bence Ágg, Barnabás Váradi, Viktória É Tóth, Regina N Nagy, Tamás G Gergely, Dorottya Gergő, András Makkos, Csilla Pelyhe, Nóra Varga, Dóra Reé, Ágota Apáti, Przemyslaw Leszek, Tamás Kovács, Nándor Nagy, Péter Ferdinandy, Edit I Buzás, Anikó Görbe, Zoltán Giricz, Zoltán V Varga
Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac phenotype
J Mol Cell Cardiol. 2021 Dec 24;165:19-30.
Rainer Schulz, Ioanna Andreadou, Derek J Hausenloy, Péter Ferdinandy
Risk factors, co-morbidities, and co-medications in cardioprotection: Importance for translation
Br J Pharmacol. 2020 Dec;177(23):5249-5251.
Ioanna Andreadou, Andreas Daiber, Gary F Baxter, Maria Felice Brizzi, Fabio Di Lisa, Nina Kaludercic, Antigone Lazou, Zoltán V Varga, Coert J Zuurbier, Rainer Schulz, Péter Ferdinandy
Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling
Free Radic Biol Med.2021 Feb 12;166:33-52.
Gerhild Euler, Fabian Locquet, Joanna Kociszewska, Yvonne Osygus, Jacqueline Heger, Rolf Schreckenberg, Klaus-Dieter Schlüter, Éva Kenyeres, Tamara Szabados, Péter Bencsik, Péter Ferdinandy, Rainer Schulz
Matrix Metalloproteinases Repress Hypertrophic Growth in Cardiac Myocytes
Cardiovasc Drugs Ther. 2021 Jan 5.
Ioanna Andreadou, Maria Tsoumani, Gemma Vilahur, Ignatios Ikonomidis, Lina Badimon, Zoltán V Varga, Péter Ferdinandy, Rainer Schulz
PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation
Front Physiol. 2020 Nov 12;11:602497.
Gábor B Brenner, Zoltán Giricz, Rita Garamvölgyi, András Makkos, Zsófia Onódi, Nabil V Sayour, Tamás G Gergely, Tamás Baranyai, Örs Petneházy, Dénes Kőrösi, Gergő P. Szabó, Hajnalka Vago, Zsófia Dohy, Csilla Czimbalmos, Béla Merkely, Swetlana Boldin-Adamsky, Elena Feinstein, Iván G Horváth, Péter Ferdinandy
Post-myocardial infarction heart failure in closed-chest coronary occlusion/reperfusion model in Göttingen minipigs and Landrace pigs
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Dániel Kucsera, Viktória E Tóth, Dorottya Gergő, Imre Vörös, Zsófia Onódi, Anikó Görbe, Péter Ferdinandy, Zoltán V Varga
Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice
Front Physiol. 2021 Feb 22;12:609465.
Dora Szabo, Zsolt Sarszegi, Beata Polgar, Eva Saghy, Adam Nemeth, Dora Reglodi, Andras Makkos, Aniko Gorbe, Zsuzsanna Helyes, Peter Ferdinandy, Robert Herczeg, Attila Gyenesei, Attila Cziraki, Andrea Tamas
PACAP-38 in Acute ST-Segment Elevation Myocardial Infarction in Humans and Pigs: A Translational Study
Int J Mol Sci. 2021 Mar 12;22(6):2883.
Lina Badimon, Emma L Robinson, Amela Jusic, Irina Carpusca, Leon J de Windt, Costanza Emanueli, Péter Ferdinandy, Wei Gu, Mariann Gyöngyösi, Matthias Hackl, Kanita Karaduzovic-Hadziabdic, Mitja Lustrek, Fabio Martelli, Eric Nham, Ines Potočnjak, Venkata Satagopam, Reinhard Schneider, Thomas Thum, Yvan Devaux, EU-CardioRNA COST Action CA17129
Cardiovascular rna markers and artificial intelligence may improve covid-19 outcome: position paper from the eu-cardiorna cost action ca17129
Cardiovasc Res. 2021 Apr 11;cvab094.
Attila Oláh, Bálint András Barta, Alex Ali Sayour, Mihály Ruppert, Eszter Virág-Tulassay, Julianna Novák, Zoltán V Varga, Péter Ferdinandy, Béla Merkely, Tamás Radovits
Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity
Antioxidants (Basel). 2021 Mar 15;10(3):452.
Bernadette Lázár, Szilvia B László, Barbara Hutka, András S Tóth, Amir Mohammadzadeh, Eszter Berekméri, Bence Ágg, Mihály Balogh, Viktor Sajtos, Kornél Király, Mahmoud Al-Khrasani, Anna Földes, Gábor Varga, Nóra Makra, Eszter Ostorházi, Dóra Szabó, Balázs Ligeti, Ágnes Kemény, Zsuzsanna Helyes, Péter Ferdinandy, Klára Gyires, Zoltán S Zádori
A comprehensive time course and correlation analysis of indomethacin-induced inflammation, bile acid alterations and dysbiosis in the rat small intestine
Biochem Pharmacol. 2021 May 1;190:114590.
András Makkos, Bence Ágg, Balázs Petrovich, Zoltán V Varga, Anikó Görbe, Péter Ferdinandy
Systematic review and network analysis of microRNAs involved in cardioprotection against myocardial ischemia/reperfusion injury and infarction: involvement of redox signalling
Free Radic Biol Med. 2021 May 6;S0891-5849(21)00280-X.
Vladislav Pajović, Csenger Kovácsházi, Marija Kosić, Marko Vasić, Ljiljana Đukić, Gábor B Brenner, Zoltán Giricz, Dragana Bajić, Péter Ferdinandy, Nina Japundžić-Žigon
Phenomapping for classification of doxorubicin-induced cardiomyopathy in rats
Toxicol Appl Pharmacol. 2021 May 17;423:115579.
Heerajnarain Bulluck, Valeria Paradies, Emanuele Barbato, Andreas Baumbach, Hans Erik Bøtker, Davide Capodanno, Raffaele De Caterina, Claudio Cavallini, Sean M Davidson, Dmitriy N Feldman, Péter Ferdinandy, Sebastiano Gili, Mariann Gyöngyösi, Vijay Kunadian, Sze-Yuan Ooi, Rosalinda Madonna, Michael Marber, Roxana Mehran, Gjin Ndrepepa, Cinzia Perrino, Stefanie Schüpke, Johanne Silvain, Joost P G Sluijter, Giuseppe Tarantini, Gabor G Toth, Linda W Van Laake, Clemens von Birgelen, Michel Zeitouni, Allan S Jaffe, Kristian Thygesen, Derek J Hausenloy
Prognostically relevant periprocedural myocardial injury and infarction associated with percutaneous coronary interventions: a Consensus Document of the ESC Working Group on Cellular Biology of the Heart and European Association of Percutaneous Cardiovascular Interventions (EAPCI)
Eur Heart J. 2021 May 31;ehab271.
Barbara Hutka, Bernadette Lázár, András S Tóth, Bence Ágg, Szilvia B László, Nóra Makra, Balázs Ligeti, Bálint Scheich, Kornél Király, Mahmoud Al-Khrasani, Dóra Szabó, Péter Ferdinandy, Klára Gyires, Zoltán S Zádori
The Nonsteroidal Anti-Inflammatory Drug Ketorolac Alters the Small Intestinal Microbiota and Bile Acids Without Inducing Intestinal Damage or Delaying Peristalsis in the Rat
Front Pharmacol. 2021 Jun 4;12:664177.
Maurizio Pesce, Piergiuseppe Agostoni, Hans-Erik Bøtker, Bianca Brundel, Sean M Davidson, Raffaele De Caterina, Peter Ferdinandy, Henrique Girao, Mariann Gyöngyösi, Jean-Sebastien Hulot, Sandrine Lecour, Cinzia Perrino, Rainer Schulz, Joost P G Sluijter, Sabine Steffens, Ivan Tancevski, Can Gollmann-Tepeköylü, Carsten Tschöpe, Sophie van Linthout, Rosalinda Madonna
COVID-19 related cardiac complications – from clinical evidences to basic mechanisms. Opinion paper of the ESC Working Group on Cellular Biology of the Heart
Cardiovasc Res. 2021 Jun 12;cvab201.
Zsófia Onódi, Mihály Ruppert, Dániel Kucsera, Alex Ali Sayour, Viktória E Tóth, Gábor Koncsos, Julianna Novák, Gábor B Brenner, András Makkos, Tamás Baranyai, Zoltán Giricz, Anikó Görbe, Przemyslaw Leszek, Mariann Gyöngyösi, Iván G Horváth, Rainer Schulz, Béla Merkely, Péter Ferdinandy, Tamás Radovits, Zoltán V Varga
AIM2-driven inflammasome activation in heart failure
Cardiovasc Res. 2021 Jun 12;cvab202.
Beáta Róka, Pál Tod, Tamás Kaucsár, Éva Nóra Bukosza, Imre Vörös, Zoltán V Varga, Balázs Petrovich, Bence Ágg, Péter Ferdinandy, Gábor Szénási, Péter Hamar
Delayed Contralateral Nephrectomy Halted Post-Ischemic Renal Fibrosis Progression and Inhibited the Ischemia-Induced Fibromir Upregulation in Mice
Biomedicines. 2021 Jul 14;9(7):815.
Sandrine Lecour, Ioanna Andreadou, Hans Erik Bøtker, Sean M Davidson, Gerd Heusch, Marisol Ruiz-Meana, Rainer Schulz, Coert J Zuurbier, Péter Ferdinandy, Derek J Hausenloy, on behalf of the European Union-CARDIOPROTECTION COST ACTION CA16225
IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action
Basic Res Cardiol. 2021 Sep 13;116(1):52.
S Lecour, B C Du Pré, H E Bøtker, B J J M Brundel, A Daiber, S M Davidson, P Ferdinandy, H Girao, C Gollmann-Tepeköylü, M Gyöngyösi, D J Hausenloy, R Madonna, M Marber, C Perrino, M Pesce, R Schulz, J P G Sluijter, S Steffens, S Van Linthout, M E Young, L W Van Laake
Circadian rhythms in ischaemic heart disease. Key aspects for preclinical and translational research: Position paper of the ESC Working Group on Cellular Biology of the Heart
Cardiovasc Res. 2021 Sep 10;cvab293.
Brenner GB, Makkos A, Nagy CT, Onódi Z, Sayour NV, Gergely TG, Kiss B, Görbe A, Sághy É, Zádori ZS, Lázár B, Baranyai T, Varga RS, Husti Z, Varró A, Tóthfalusi L, Schulz R, Baczkó I, Giricz Z, Ferdinandy P.
Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion.
Cells. 2020 Feb 26;9(3):E551.
Ferdinandy P, Yoneda F, Muraoka S, Fürst S, Gyires K, Miklya I.
Geroprotection in the future. In memoriam of Joseph Knoll: The selegiline story continues.
Eur J Pharmacol. 2020 Feb 5;868:172793
van Esbroeck ACM, Varga ZV, Di X, van Rooden EJ, Tóth VE, Onódi Z, Kuśmierczyk M, Leszek P, Ferdinandy P, Hankemeier T, van der Stelt M, Pacher P.
Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system.
Pharmacol Res. 2020 Jan;151:104578.
Makkos A, Szántai Á, Pálóczi J, Pipis J, Kiss B, Poggi P, Ferdinandy P, Chatgilialoglu A, Görbe A.
A Comorbidity Model of Myocardial Ischemia/Reperfusion Injury and Hypercholesterolemia in Rat Cardiac Myocyte Cultures.
Front Physiol. 2020 Jan 9;10:1564
Marija Gredic, Isabel Blanco, Gabor Kovacs, Zsuzsanna Helyes, Péter Ferdinandy, Horst Olschewski, Joan Albert Barberà, Norbert Weissmann
Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease
Br J Pharmacol, 2020 Jan 23[Online ahead of print]
Péter Bencsik, Kamilla Gömöri, Tamara Szabados, Péter Sántha, Zsuzsanna Helyes, Gábor Jancsó, Péter Ferdinandy, Anikó Görbe
Myocardial Ischemia Reperfusion Injury and Cardioprotection in the Presence of Sensory Neuropathy: Therapeutic Options
Br J Pharmacol, 2020 Feb 14[Online ahead of print]
Schreckenberg R, Klein J, Kutsche HS, Schulz R, Gömöri K, Bencsik P, Benczik B, Ágg B, Sághy É, Ferdinandy P, Schlüter KD.
Ischaemic post-conditioning in rats: Responder and non-responder differ in transcriptome of mitochondrial proteins.
J Cell Mol Med. 2020 Apr 16. doi: 10.1111/jcmm.15209. Epub ahead of print
Sághy É, Vörös I, Ágg B, Kiss B, Koncsos G, Varga ZV, Görbe A, Giricz Z, Schulz R, Ferdinandy P.
Cardiac miRNA Expression and their mRNA Targets in a Rat Model of Prediabetes.
Int J Mol Sci. 2020 Mar 20;21(6):2128.
Parini P, Altucci L, Balligand JL, Baumbach PDJ, Ferdinandy P, Filetti S, Maron BM, Petrillo E, Silverman EK, Barabasi AL, Loscalzo J; International Network Medicine Consortium.
The Network Medicine Imperative and the Need for an International Network Medicine Consortium.
Am J Med. 2020 Apr 19:S0002-9343(20)30340-5. doi: 10.1016/j.amjmed.2020.03.034. Epub ahead of print.
Perrino C, Ferdinandy P, Bøtker HE, Brundel BJJM, Collins P, Davidson SM, den Ruijter HM, Engel FB, Gerdts E, Girao H, Gyöngyösi M, Hausenloy DJ, Lecour S, Madonna R, Marber M, Murphy E, Pesce M, Regitz-Zagrosek V, Sluijter JPG, Steffens S, Gollmann-Tepeköylü C, Van Laake LW, Van Linthout S, Schulz R, Ytrehus K.
Improving Translational Research in Sex-specific Effects of Comorbidities and Risk Factors in Ischemic Heart Disease and Cardioprotection: Position Paper and Recommendations of the ESC Working Group on Cellular Biology of the Heart.
Cardiovasc Res. 2020 Jun 2:cvaa155.
Giricz Z, Makkos A, Schreckenberg R, Pöling J, Lörchner H, Kiss K, Bencsik P, Braun T, Schulz R, Ferdinandy P, Schlüter KD.
Swiprosin-1/EFhD-2 Expression in Cardiac Remodeling and Post-Infarct Repair: Effect of Ischemic Conditioning.
Int J Mol Sci. 2020 May 9;21(9):3359.
Ruiz-Meana M, Bou-Teen D, Ferdinandy P, Gyongyosi M, Pesce M, Perrino C, Schulz R, Sluijter J, Tocchetti CG, Thum T, Madonna R.
Cardiomyocyte ageing and cardioprotection: Consensus Document from the ESC Working Groups Cell Biology of the Heart and Myocardial Function.
Cardiovasc Res. 2020 May 8:cvaa132.
Andreadou I, Schulz R, Papapetropoulos A, Turan B, Ytrehus K, Ferdinandy P, Daiber A, Di Lisa F.
The role of mitochondrial reactive oxygen species, NO and H2 S in ischaemia/reperfusion injury and cardioprotection.
J Cell Mol Med. 2020 Jun;24(12):6510-6522.
Madonna R, Doria V, Görbe A, Cocco N, Ferdinandy P, Geng YJ, Pierdomenico SD, De Caterina R.
Co-expression of glycosylated aquaporin-1 and transcription factor NFAT5 contributes to aortic stiffness in diabetic and atherosclerosis-prone mice.
J Cell Mol Med. 2020 Mar;24(5):2857-2865.
Tocchetti CG, Ameri P, de Boer RA, D’Alessandra Y, Russo M, Sorriento D, Ciccarelli M, Kiss B, Bertrand L, Dawson D, Falcao-Pires I, Giacca M, Hamdani N, Linke WA, Mayr M, van der Velden J, Zacchigna S, Ghigo A, Hirsch E, Lyon AR, Görbe A, Ferdinandy P, Madonna R, Heymans S, Thum T.
Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs. Novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart.
Cardiovasc Res. 2020 Jul 19:cvaa222.
Szabados T, Gömöri K, Pálvölgyi L, Görbe A, Baczkó I, Helyes Z, Jancsó G, Ferdinandy P, Bencsik P.
Capsaicin-Sensitive Sensory Nerves and the TRPV1 Ion Channel in Cardiac Physiology and Pathologies.
Int J Mol Sci. 2020 Jun 23;21(12):4472
László SB, Lázár B, Brenner GB, Makkos A, Balogh M, Al-Khrasani M, Hutka B, Mohammadzadeh A, Kemény Á, László T, Scheich B, Szabados T, Kenyeres É, Giricz Z, Bencsik P, Varga ZV, Novák J, Helyes Z, Ferdinandy P, Gyires K, Zádori ZS.
Chronic treatment with rofecoxib but not ischemic preconditioning of the myocardium ameliorates early intestinal damage following cardiac ischemia/reperfusion injury in rats.
Biochem Pharmacol. 2020 Aug;178:114099.
Ágg B, Szilveszter B, Daradics N, Benke K, Stengl R, Kolossváry M, Pólos M, Radovits T, Ferdinandy P, Merkely B, Maurovich-Horvat P, Szabolcs Z.
Increased visceral arterial tortuosity in Marfan syndrome.
Orphanet J Rare Dis. 2020 Apr 15;15(1):91.
Gömöri K, Szabados T, Kenyeres É, Pipis J, Földesi I, Siska A, Dormán G, Ferdinandy P, Görbe A, Bencsik P.
Cardioprotective Effect of Novel Matrix Metalloproteinase Inhibitors.
Int J Mol Sci. 2020 Sep 23;21(19):E6990.
Maron BA, Altucci L, Balligand JL, Baumbach J, Ferdinandy P, Filetti S, Parini P, Petrillo E, Silverman EK, Barabási AL, Loscalzo J; International Network Medicine Consortium.
A global network for network medicine.
NPJ Syst Biol Appl. 2020 Aug 31;6(1):29.
Pálóczi J, Szántai Á, Kobolák J, Bock I, Ruivo E, Kiss B, Gáspár R, Pipis J, Ocsovszki I, Táncos Z, Fehér A, Dinnyés A, Onódi Z, Madonna R, Ferdinandy P, Görbe A.
Systematic analysis of different pluripotent stem cell-derived cardiac myocytes as potential testing model for cardiocytoprotection.
Vascul Pharmacol. 2020 Oct-Nov;133-134:106781.
Zamorano JL, Gottfridsson C, Asteggiano R, Atar D, Badimon L, Bax JJ, Cardinale D, Cardone A, Feijen EAM, Ferdinandy P, López-Fernández T, Gale CP, Maduro JH, Moslehi J, Omland T, Plana Gomez JC, Scott J, Suter TM, Minotti G.
The cancer patient and cardiology.
Eur J Heart Fail. 2020 Aug 18.
Gáspár R, Gömöri K, Kiss B, Szántai Á, Pálóczi J, Varga ZV, Pipis J, Váradi B, Ágg B, Csont T, Ferdinandy P, Barteková M, Görbe A.
Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury.
Molecules. 2020 Jul 28;25(15):3426.
Peter Pečan, Szabolcs Hambalkó, Van Thai Ha, Csilla T Nagy, Csilla Pelyhe, Duško Lainšček, Bence Kenyeres, Gábor B Brenner, Anikó Görbe, Ágnes Kittel, Monika Barteková, Péter Ferdinandy, Mateja Manček-Keber, Zoltán Giricz
Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1
Int J Mol Sci. 2020 Oct 16;21(20):7687.
Angéla Kecskés, Krisztina Pohóczky, Miklós Kecskés, Zoltán V Varga, Viktória Kormos, Éva Szőke, Nóra Henn-Mike, Máté Fehér, József Kun, Attila Gyenesei, Éva Renner, Miklós Palkovits, Péter Ferdinandy, István M Ábrahám, Balázs Gaszner, Zsuzsanna Helyes
Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains
Int J Mol Sci. 2020 Oct 21;21(20):7788.
Rosalinda Madonna, Damiana Pieragostino, Claudia Rossi, Simone Guarnieri, Csilla T Nagy, Zoltán Giricz, Péter Ferdinandy, Piero Del Boccio, Maria Addolorata Mariggiò, Yong-Jian Geng, Raffaele De Caterina
Transplantation of telomerase/myocardin-co-expressing mesenchymal cells in the mouse promotes myocardial revascularization and tissue repair
Vascul Pharmacol. 2020 Oct 31;106807.
Lukovic D, Gugerell A, Zlabinger K, Winkler J, Pavo N, Baranyai T, Giricz Z, Varga ZV, Riesenhuber M, Spannbauer A, Traxler D, Jakab A, Garamvölgyi R, Petnehazy Ö, Pils D, Tóth L, Schulz R, Ferdinandy P, Gyöngyösi M.
Transcriptional Alterations by Ischaemic Postconditioning in a Pig Infarction Model: Impact on Microvascular Protection.
Int J Mol Sci. 2019 Jan 15;20(2).
Nagel F, Santer D, Stojkovic S, Kaun C, Schaefer AK, Krššák M, Abraham D, Bencsik P, Ferdinandy P, Kenyeres E, Szabados T, Wojta J, Trescher K, Kiss A, Podesser BK.
The impact of age on cardiac function and extracellular matrix component expression in adverse post-infarction remodeling in mice.
Exp Gerontol. 2019 May;119:193-202.
Ágg B, Császár A, Szalay-Bekő M, Veres DV, Mizsei R, Ferdinandy P, Csermely P, Kovács IA.
The EntOptLayout Cytoscape plug-in for the efficient visualization of major protein complexes in protein-protein interaction and signalling networks.
Bioinformatics. 2019 Nov 1;35(21):4490-4492.
Hausenloy DJ, Chilian W, Crea F, Davidson SM, Ferdinandy P, Garcia-Dorado D, van Royen N, Schulz R, Heusch G.
The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection.
Cardiovasc Res. 2019 Jun 1;115(7):1143-1155.
Horváth Á, Botz B, Kiss T, Csekő K, Kiss I, Felinger A, Szabados T, Kenyeres É, Bencsik P, Mócsai A, Ferdinandy P, Helyes Z.
Subantimicrobial Dose Doxycycline Worsens Chronic Arthritis-Induced Bone Microarchitectural Alterations in a Mouse Model: Role of Matrix Metalloproteinases?
Front Pharmacol. 2019 Mar 20;10:233.
Oláh A, Mátyás C, Kellermayer D, Ruppert M, Barta BA, Sayour AA, Török M, Koncsos G, Giricz Z, Ferdinandy P, Merkely B, Radovits T.
Sex Differences in Morphological and Functional Aspects of Exercise-Induced Cardiac Hypertrophy in a Rat Model.
Front Physiol. 2019 Jul 12;10:889.
Bencsik P, Kiss K, Ágg B, Baán JA, Ágoston G, Varga A, Gömöri K, Mendler L, Faragó N, Zvara Á, Sántha P, Puskás LG, Jancsó G, Ferdinandy P.
Sensory Neuropathy Affects Cardiac miRNA Expression Network Targeting IGF-1, SLC2a-12, EIF-4e, and ULK-2 mRNAs.
Int J Mol Sci. 2019 Feb 25;20(4).
Madonna R, Angelucci S, Di Giuseppe F, Doria V, Giricz Z, Görbe A, Ferdinandy P, De Caterina R.
Proteomic analysis of the secretome of adipose tissue-derived murine mesenchymal cells overexpressing telomerase and myocardin.
J Mol Cell Cardiol. 2019 Jun;131:171-186.
Grigorian Shamagian L, Madonna R, Taylor D, Climent AM, Prosper F, Bras-Rosario L, Bayes-Genis A, Ferdinandy P, Fernández-Avilés F, Izpisua Belmonte JC, Fuster V, Bolli R.
Perspectives on Directions and Priorities for Future Preclinical Studies in Regenerative Medicine.
Circ Res. 2019 Mar 15;124(6):938-951.
Davidson SM, Ferdinandy P, Andreadou I, Bøtker HE, Heusch G, Ibáñez B, Ovize M, Schulz R, Yellon DM, Hausenloy DJ, Garcia-Dorado D; CARDIOPROTECTION COST Action (CA16225).
Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week.
J Am Coll Cardiol. 2019 Jan 8;73(1):89-99.
Lázár B, Brenner GB, Makkos A, Balogh M, László SB, Al-Khrasani M, Hutka B, Bató E, Ostorházi E, Juhász J, Kemény Á, László T, Tiszlavicz L, Bihari Z, Giricz Z, Szabó D, Helyes Z, Ferdinandy P, Gyires K, Zádori ZS.
Lack of Small Intestinal Dysbiosis Following Long-Term Selective Inhibition of Cyclooxygenase-2 by Rofecoxib in the Rat.
Cells. 2019 Mar 15;8(3).
Tuboly E, Gáspár R, Ibor MO, Gömöri K, Kiss B, Strifler G, Hartmann P, Ferdinandy P, Bartekova M, Boros M, Görbe A.
L-Alpha-glycerylphosphorylcholine can be cytoprotective or cytotoxic in neonatal rat cardiac myocytes: a double-edged sword phenomenon.
Mol Cell Biochem. 2019 Oct;460(1-2):195-203
Madonna R, Balistreri CR, De Rosa S, Muscoli S, Selvaggio S, Selvaggio G, Ferdinandy P, De Caterina R.
Impact of Sex Differences and Diabetes on Coronary Atherosclerosis and Ischemic Heart Disease.
J Clin Med. 2019 Jan 16;8(1).
Andreadou I, Schulz R, Badimon L, Adameová A, Kleinbongard P, Lecour S, Nikolaou PE, Falcão-Pires I, Vilahur G, Woudberg N, Heusch G, Ferdinandy P.
Hyperlipidaemia and cardioprotection: Animal models for translational studies.
Br J Pharmacol. 2019 Nov 26.
Bukosza EN, Kaucsár T, Godó M, Lajtár E, Tod P, Koncsos G, Varga ZV, Baranyai T, Nguyen MT, Schachner H, Sőti C, Ferdinandy P, Giricz Z, Szénási G, Hamar P.
Glomerular Collagen Deposition and Lipocalin-2 Expression Are Early Signs of Renal Injury in Prediabetic Obese Rats.
Int J Mol Sci. 2019 Aug 30;20(17).
Madonna R, Van Laake LW, Botker HE, Davidson SM, De Caterina R, Engel FB, Eschenhagen T, Fernandez-Aviles F, Hausenloy DJ, Hulot JS, Lecour S, Leor J, Menasché P, Pesce M, Perrino C, Prunier F, Van Linthout S, Ytrehus K, Zimmermann WH, Ferdinandy P, Sluijter JPG.
ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure.
Cardiovasc Res. 2019 Mar 1;115(3):488-500.
Lajtai K, Nagy CT, Tarszabó R, Benkő R, Hadjadj L, Sziva RE, Gerszi D, Bányai B, Ferdinandy P, Nádasy GL, Giricz Z, Horváth EM, Várbíró S.
Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome.
Biomolecules. 2019 Sep 10;9(9).
Spannbauer A, Traxler D, Lukovic D, Zlabinger K, Winkler J, Gugerell A, Ferdinandy P, Hausenloy DJ, Pavo N, Emmert MY, Hoerstrup SP, Jakab A, Gyöngyösi M, Riesenhuber M.
Effect of Ischemic Preconditioning and Postconditioning on Exosome-Rich Fraction microRNA Levels, in Relation with Electrophysiological Parameters and Ventricular Arrhythmia in Experimental Closed-Chest Reperfused Myocardial Infarction.
Int J Mol Sci. 2019 Apr 30;20(9).
Poz D, De Falco E, Pisano C, Madonna R, Ferdinandy P, Balistreri CR.
Diagnostic and Prognostic Relevance of Red Blood Cell Distribution Width for Vascular Aging and Cardiovascular Diseases.
Rejuvenation Res. 2019 Apr;22(2):146-162.
Davidson SM, Andreadou I, Barile L, Birnbaum Y, Cabrera-Fuentes HA, Cohen MV, Downey JM, Girao H, Pagliaro P, Penna C, Pernow J, Preissner KT, Ferdinandy P.
Circulating blood cells and extracellular vesicles in acute cardioprotection.
Cardiovasc Res. 2019 Jun 1;115(7):1156-1166.
Gomes CPC, Ágg B, Andova A, Arslan S, Baker A, Barteková M, Beis D, Betsou F, Wettinger SB, Bugarski B, Condorelli G, Silva GJJD, Danilin S, de Gonzalo-Calvo D, Buil A, Carmo-Fonseca M, Enguita FJ, Felekkis K, Ferdinandy P, Gyöngyösi M, Hackl M, Karaduzovic-Hadziabdic K, Hellemans J, Heymans S, Hlavackova M, Hoydal MA, Jankovic A, Jusic A, Kardassis D, Kerkelä R, Kuster GM, Lakkisto P, Leszek P, Lustrek M, Maegdefessel L, Martelli F, Novella S, O’Brien T, Papaneophytou C, Pedrazzini T, Pinet F, Popescu O, Potočnjak I, Robinson E, Sasson S, Scholz M, Simionescu M, Stoll M, Varga ZV, Vinciguerra M, Xuereb A, Yilmaz MB, Emanueli C, Devaux Y, on behalf of the EU-CardioRNA COST Action (CA17129).
Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129.
Noncoding RNA. 2019 Mar 29;5(2).
Hausenloy DJ, Bøtker HE, Ferdinandy P, Heusch G, Ng GA, Redington A, Garcia-Dorado D.
Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection.
Cardiovasc Res. 2019 Jun 1;115(7):1167-1177
Ferdinandy P, Baczkó I, Bencsik P, Giricz Z, Görbe A, Pacher P, Varga ZV, Varró A, Schulz R.
Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications.
Eur Heart J. 2019 Jun 7;40(22):1771-1777.
Sluijter JPG, Davidson SM, Boulanger CM, Buzás EI, de Kleijn DPV, Engel FB, Giricz Z, Hausenloy DJ, Kishore R, Lecour S, Leor J, Madonna R, Perrino C, Prunier F, Sahoo S, Schiffelers RM, Schulz R, Van Laake LW, Ytrehus K, Ferdinandy P.
Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology.
Cardiovasc Res. 2018 Jan 1;114(1):19-34.
Gohar A, de Kleijn DPV, Hoes AW, Rutten FH, Hilfiker-Kleiner D, Ferdinandy P, Sluijter JPG, den Ruijter HM.
Vascular extracellular vesicles in comorbidities of heart failure with preserved ejection fraction in men and women: The hidden players. A mini review.
Vascul Pharmacol. 2018 Dec;111:1-6.
Schulz R, Ágg B, Ferdinandy P.
Survival pathways in cardiac conditioning: individual data vs. meta-analyses. What do we learn?
Basic Res Cardiol. 2017 Nov 21;113(1):4.
Nagy CT, Koncsos G, Varga ZV, Baranyai T, Tuza S, Kassai F, Ernyey AJ, Gyertyán I, Király K, Oláh A, Radovits T, Merkely B, Bukosza N, Szénási G, Hamar P, Mathé D, Szigeti K, Pelyhe C, Jelemenský M, Onódi Z, Helyes Z, Schulz R, Giricz Z, Ferdinandy P.
Selegiline reduces adiposity induced by high-fat, high-sucrose diet in male rats.
Br J Pharmacol. 2018 Sep;175(18):3713-3726.
Bøtker HE, Hausenloy D, Andreadou I, Antonucci S, Boengler K, Davidson SM, Deshwal S, Devaux Y, Di Lisa F, Di Sante M, Efentakis P, Femminò S, García-Dorado D, Giricz Z, Ibanez B, Iliodromitis E, Kaludercic N, Kleinbongard P, Neuhäuser M, Ovize M, Pagliaro P, Rahbek-Schmidt M, Ruiz-Meana M, Schlüter KD, Schulz R, Skyschally A, Wilder C, Yellon DM, Ferdinandy P, Heusch G.
Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection.
Basic Res Cardiol. 2018 Aug 17;113(5):39.
Koncsos G, Varga ZV, Baranyai T, Ferdinandy P, Schulz R, Giricz Z, Boengler K.
Nagarse treatment of cardiac subsarcolemmal and interfibrillar mitochondria leads to artefacts in mitochondrial protein quantification.
J Pharmacol Toxicol Methods. 2018 May – Jun;91:50-58.
Varga ZV, Ágg B, Ferdinandy P.
miR-125b is a protectomiR: A rising star for acute cardioprotection.
J Mol Cell Cardiol. 2018 Feb;115:51-53
Ágg B, Baranyai T, Makkos A, Vető B, Faragó N, Zvara Á, Giricz Z, Veres DV, Csermely P, Arányi T, Puskás LG, Varga ZV, Ferdinandy P.
MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium.
Sci Rep. 2018 Jul 4;8(1):10134.
Heger J, Bornbaum J, Würfel A, Hill C, Brockmann N, Gáspár R, Pálóczi J, Varga ZV, Sárközy M, Bencsik P, Csont T, Török S, Kojonazarov B, Schermuly RT, Böngler K, Parahuleva M, Ferdinandy P, Schulz R, Euler G.
JDP2 overexpression provokes cardiac dysfunction in mice.
Sci Rep. 2018 May 16;8(1):7647
Onódi Z, Pelyhe C, Terézia Nagy C, Brenner GB, Almási L, Kittel Á, Manček-Keber M, Ferdinandy P, Buzás EI, Giricz Z.
Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.
Front Physiol. 2018 Oct 23;9:1479.
Sluijter JPG, Davidson SM, Boulanger CM, Buzás EI, de Kleijn DPV, Engel FB, Giricz Z, Hausenloy DJ, Kishore R, Lecour S, Leor J, Madonna R, Perrino C, Prunier F, Sahoo S, Schiffelers RM, Schulz R, Van Laake LW, Ytrehus K, Ferdinandy P.
Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology.
Cardiovasc Res. 2018 Jan 1;114(1):19-34
Schiattarella GG, Madonna R, Van Linthout S, Thum T, Schulz R, Ferdinandy P, Perrino C.
Epigenetic modulation of vascular diseases: Assessing the evidence and exploring the opportunities.
Vascul Pharmacol. 2018 Mar 14.
Poz D, De Falco E, Pisano C, Madonna R, Ferdinandy P, Balistreri CR.
Diagnostic and Prognostic Relevance of Red Blood Cell Distribution Width for Vascular Aging and Cardiovascular Diseases.
Rejuvenation Res. 2019 Apr;22(2):146-162.
Bencsik P, Kupai K, Görbe A, Kenyeres É, Varga ZV, Pálóczi J, Gáspár R, Kovács L, Weber L, Takács F, Hajdú I, Fabó G, Cseh S, Barna L, Csont T, Csonka C, Dormán G, Ferdinandy P.
Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection.
Front Pharmacol. 2018 Apr 5;9:296.
Varga VZ., Bence Á., Ferdinandy P.
miR-125b is a protectomiR: A rising star for acute cardioprotection
J Mol Cell Cardiol. 2017 Dec 30. pii: S0022-2828(17)30366-8.
Schreckenberg R, Bencsik P, Weber M, Abdallah Y, Csonka C, Gömöri K, Kiss K, Pálóczi J, Pipis J, Sárközy M, Ferdinandy P, Schulz R, Schlüter KD.
Adverse Effects on β-Adrenergic Receptor Coupling: Ischemic Postconditioning Failed to Preserve Long-Term Cardiac Function.
J Am Heart Assoc. 2017 Dec 22;6(12).
Boengler K, Bencsik P, Palóczi J, Kiss K, Pipicz M, Pipis J, Ferdinandy P, Schlüter KD, Schulz R.
Lack of Contribution of p66shc and Its Mitochondrial Translocation to Ischemia-Reperfusion Injury and Cardioprotection by Ischemic Preconditioning.
Front Physiol. 2017 Oct 5;8:733.
Leybaert L, Lampe PD, Dhein S, Kwak BR, Ferdinandy P, Beyer EC, Laird DW, Naus CC, Green CR, Schulz R.
Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications.
Pharmacol Rev. 2017 Oct;69(4):396-478.
Giricz Z, Varga ZV, Koncsos G, Nagy CT, Görbe A, Mentzer RM Jr, Gottlieb RA, Ferdinandy P.
Autophagosome formation is required for cardioprotection by chloramphenicol.
Life Sci. 2017 Oct 1;186:11-16.
Thielmann M, Sharma V, Al-Attar N, Bulluck H, Bisleri G, Bunge JJH, Czerny M, Ferdinandy P, Frey UH, Heusch G, Holfeld J, Kleinbongard P, Kunst G, Lang I, Lentini S, Madonna R, Meybohm P, Muneretto C, Obadia JF, Perrino C, Prunier F, Sluijter JPG, Van Laake LW, Sousa-Uva M, Hausenloy DJ.
ESC Joint Working Groups on Cardiovascular Surgery and the Cellular Biology of the Heart Position Paper: Perioperative myocardial injury and infarction in patients undergoing coronary artery bypass graft surgery.
Eur Heart J. 2017 Aug 14;38(31):2392-2407.
Andreadou I, Iliodromitis EK, Lazou A, Görbe A, Giricz Z, Schulz R, Ferdinandy. P.
Effect of hypercholesterolaemia on myocardial function, ischaemia-reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning.
Br J Pharmacol. 2017 Jan 6.
Pavo N, Lukovic D, Zlabinger K, Lorant D, Goliasch G, Winkler J, Pils D, Auer K, Ankersmit HJ, Giricz Z, Sárközy M, Jakab A, Garamvölgyi R, Emmert MY, Hoerstrup SP, Hausenloy DJ, Ferdinandy P, Maurer G, Gyöngyösi M.
Intrinsic remote conditioning of the myocardium as a comprehensive cardiac response to ischemia and reperfusion.
Oncotarget. 2017 Jun 12;8(40):67227-67240.
Daiber A, Di Lisa F, Ferdinandy P.
Pharmacology of oxidative stress: translational opportunities.
Br J Pharmacol. 2017 Jun;174(12):1511-1513.
Hausenloy DJ, Garcia-Dorado D, Bøtker HE, Davidson SM, Downey J, Engel FB, Jennings R, Lecour S, Leor J, Madonna R, Ovize M, Perrino C, Prunier F, Schulz R, Sluijter JPG, Van Laake LW, Vinten-Johansen J, Yellon DM, Ytrehus K, Heusch G, Ferdinandy P.
Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.
Cardiovasc Res. 2017 May 1;113(6):564-585.
Baranyai T, Giricz Z, Varga ZV, Koncsos G, Lukovic D, Makkos A, Sárközy M, Pávó N, Jakab A, Czimbalmos C, Vágó H, Ruzsa Z, Tóth L, Garamvölgyi R, Merkely B, Schulz R, Gyöngyösi M, Ferdinandy P.
In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning,
postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature.
J Transl Med. 2017 Apr 1;15(1):67.
Szobi A, Gonçalvesová E, Varga ZV, Leszek P, Kuśmierczyk M, Hulman M, Kyselovič J, Ferdinandy P, Adameová A.
Analysis of necroptotic proteins in failing human hearts.
J Transl Med. 2017 Apr 28;15(1):86.
Schulz R, Ágg B, Ferdinandy P.
Survival pathways in cardiac conditioning: individual data vs. meta-analyses. What do we learn?
Basic Res Cardiol. 2017 Nov 21;113(1):4.
Bencsik P, Bartekova M, Görbe A, Kiss K, Pálóczi J, Radosinska J, Szűcs G, Ferdinandy P.
MMP Activity Detection in Zymograms.
Methods Mol Biol. 2017;1626:53-70
Kemény Á, Csekő K, Szitter I, Varga ZV, Bencsik P, Kiss K, Halmosi R, Deres L, Erős K, Perkecz A, Kereskai L, László T, Kiss T, Ferdinandy P, Helyes Z.
Integrative characterization of chronic cigarette smoke-induced cardiopulmonary comorbidities in a mouse model.
Environ Pollut. 2017 Oct;229:746-759.
Perrino C, Barabási AL, Condorelli G, Davidson SM, De Windt L, Dimmeler S, Engel FB, Hausenloy DJ, Hill JA, Van Laake LW, Lecour S, Leor J, Madonna R, Mayr M, Prunier F, Sluijter JP, Schulz R, Thum T, Ytrehus K, Ferdinandy P.
Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for
diagnosis and therapy of the ischemic heart?
Cardiovasc Res. 2017 Apr 29.
Baranyai T, Giricz Z, Varga ZV, Koncsos G, Lukovic D, Makkos A, Sárközy M, Pávó N, Jakab A, Czimbalmos C, Vágó H, Ruzsa Z, Tóth L, Garamvölgyi R, Merkely B, Schulz R, Gyöngyösi M, Ferdinandy P.
In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature.
J Transl Med. 2017 Apr 1;15(1):67.
Giricz Z, Koncsos G, Rajtík T, Varga ZV, Baranyai T, Csonka C, Szobi A, Adameová A, Gottlieb RA, Ferdinandy P.
Hypercholesterolemia downregulates autophagy in the rat heart.
Lipids Health Dis. 2017 Mar 23;16(1):60.
Perrino C, Barabási AL, Condorelli G, Davidson SM, De Windt L, Dimmeler S, Engel FB, Hausenloy DJ, Hill JA, Van Laake LW, Lecour S, Leor J, Madonna R, Mayr M, Prunier F, Sluijter JPG, Schulz R, Thum T, Ytrehus K, Ferdinandy P.
Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.
Cardiovasc Res. 2017 Jun 1;113(7):725-736.
Varga ZV, Pipicz M, Baán JA, Baranyai T, Koncsos G, Leszek P, Kuśmierczyk M, Sánchez-Cabo F, García-Pavía P, Brenner GJ, Giricz Z, Csont T, Mendler L, Lara-Pezzi E, Pacher P, Ferdinandy P.
Alternative Splicing of NOX4 in the Failing Human Heart.
Front Physiol. 2017 Nov 22;8:935.
Rajtik T, Carnicka S, Szobi A, Giricz Z, O-Uchi J, Hassova V, Svec P, Ferdinandy P, Ravingerova T, Adameova A.
Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: A role of angiotensin AT1 receptor-NOX2 signaling axis.
Eur J Pharmacol. 2016 Jan 15;771:114-22. doi: 10.1016/j.ejphar.2015.12.024. Epub 2015 Dec 13.
Di Lisa F, Giorgio M, Ferdinandy P, Schulz R.
New aspects of p66Shc in ischemia reperfusion injury and cardiovascular diseases.
Br J Pharmacol. 2016 Mar 15. doi: 10.1111/bph.13478. [Epub ahead of print]
Madonna R, Van Laake LW, Davidson SM, Engel FB, Hausenloy DJ, Lecour S, Leor J, Perrino C, Schulz R, Ytrehus K, Landmesser U, Mummery CL, Janssens S, Willerson J, Eschenhagen T, Ferdinandy P, Sluijter JP.
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure.
Eur Heart J. 2016 Apr 7. pii: ehw113. [Epub ahead of print] Review.
Sárközy M, Szűcs G, Fekete V, Pipicz M, Éder K, Gáspár R, Sója A, Pipis J, Ferdinandy P, Csonka C, Csont T.
Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats.
Cardiovasc Diabetol. 2016 Aug 5;15(1):110.
Brockhoff B, Schreckenberg R, Forst S, Heger J, Bencsik P, Kiss K, Ferdinandy P, Schulz R, Schlüter KD.
Effect of nitric oxide deficiency on the pulmonary PTHrP system.
J Cell Mol Med. 2016 Aug 31.
Kiss K, Csonka C, Pálóczi J, Pipis J, Görbe A, Kocsis GF, Murlasits Z, Sárközy M, Szűcs G, Holmes CP, Pan Y, Bhandari A, Csont T, Shamloo M, Woodburn KW, Ferdinandy P, Bencsik P.
Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats.
Pharmacol Res. 2016 Aug 10;113(Pt A):62-70.
Schreckenberg R, Weber P, Cabrera-Fuentes HA, Steinert I, Preissner KT, Bencsik P, Sárközy M, Csonka C, Ferdinandy P, Schulz R, Schlüter KD.
Mechanism and consequences of the shift in cardiac arginine metabolism following ischaemia and reperfusion in rats.
Thromb Haemost. 2015 Mar;113(3):482-93
Baán JA, Varga ZV, Leszek P, Kuśmierczyk M, Baranyai T, Dux L, Ferdinandy P, Braun T, Mendler L.
Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study.
J Transl Med. 2015 Jan 16;13:1.
Csont T, Murlasits Z, Ménesi D, Kelemen JZ, Bencsik P, Pipicz M, Fekete V, Zvara Á, Puskás LG, Ferdinandy P.
Tissue-specific Gene Expression in Rat Hearts and Aortas in a Model of Vascular Nitrate Tolerance.
J Cardiovasc Pharmacol. 2015 May;65(5):485-93
Kirca M, Kleinbongard P, Soetkamp D, Heger J, Csonka C, Ferdinandy P, Schulz R.
Interaction between connexin 43 and nitric oxide synthase in mice heart mitochondria.
J Cell Mol Med. 2015 Apr;19(4):815-25.
Varga ZV, Giricz Z, Bencsik P, Madonna R, Gyöngyösi M, Schulz R, Mayr M, Thum T, Puskás LG, Ferdinandy P.
Functional genomics of cardioprotection by ischemic conditioning and the influence of comorbid conditions: implications in target identification.
Curr Drug Targets. 2015 Apr 27.
Bencsik P, Sasi V, Kiss K, Kupai K, Kolossváry M, Maurovich-Horvat P, Csont T, Ungi I, Merkely B, Ferdinandy P.
Serum lipids and cardiac function correlate with nitrotyrosine and MMP activity in coronary artery disease patients.
Eur J Clin Invest. 2015 May 5.
Madonna R, Cadeddu C, Deidda M, Giricz Z, Madeddu C, Mele D, Monte I, Novo G, Pagliaro P, Pepe A, Spallarossa P, Tocchetti CG, Varga ZV, Zito C, Geng YJ, Mercuro G, Ferdinandy P.
Cardioprotection by gene therapy: A review paper on behalf of the Working Group on Drug Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology.
Int J Cardiol. 2015 Jul 15;191:203-210.
Schreckenberg R, da Costa Rebelo M, Deten A, Weber M, Rohrbach S, Pipicz M, Csonka C, Ferdinandy P, Schulz R, Schlüter KD.
Specific Mechanisms underlying Right Heart Failure: The missing Upregulation of Superoxide Dismutase-2 and its decisive Role in Antioxidative Defense.
Antioxid Redox Signal. 2015 May 15.
Schulz R, Görge PM, Görbe A, Ferdinandy P, Lampe PD, Leybaert L.
Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection.
Pharmacol Ther. 2015 Jun 11. pii: S0163-7258(15)00120-5.
Sárközy M, Szűcs G, Pipicz M, Zvara Á, Éder K, Fekete V, Szűcs C, Bárkányi J, Csonka C, Puskás LG, Kónya C, Ferdinandy P, Csont T.
The effect of a preparation of minerals, vitamins and trace elements on the cardiac gene expression pattern in male diabetic rats.
Cardiovasc Diabetol. 2015 Jun 28;14:85. doi: 10.1186/s12933-015-0248-6.
Görbe A, Eder A, Varga ZV, Pálóczi J, Hansen A, Ferdinandy P, Eschenhagen T.
Protection by the NO-Donor SNAP and BNP against Hypoxia/Reoxygenation in Rat Engineered Heart Tissue.
PLoS One. 2015 Jul 6;10(7):e0132186. doi: 10.1371/journal.pone.0132186. eCollection 2015.
Madonna R, Petrov L, Teberino MA, Manzoli L, Karam JP, Renna FV, Ferdinandy P, Montero-Menei CN, Ylä-Herttuala S, De Caterina R.
Transplantation of adipose tissue mesenchymal cells conjugated with VEGF-releasing microcarriers promotes repair in murine myocardial infarction.
Cardiovasc Res. 2015 Oct 1;108(1):39-49. doi: 10.1093/cvr/cvv197. Epub 2015 Jul 17.
Varga ZV, Ferdinandy P, Liaudet L, Pacher P.
Drug-induced mitochondrial dysfunction and cardiotoxicity.
Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1453-67. doi: 10.1152/ajpheart.00554.2015. Epub 2015 Sep 18. Review.
Baranyai T, Nagy CT, Koncsos G, Onódi Z, Károlyi-Szabó M, Makkos A, Varga ZV, Ferdinandy P, Giricz Z.
Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning.
Cardiovasc Diabetol. 2015 Nov 18;14:151. doi: 10.1186/s12933-015-0313-1.
Baranyai T, Herczeg K, Onódi Z, Voszka I, Módos K, Marton N, Nagy G, Mäger I, Wood MJ, El Andaloussi S, Pálinkás Z, Kumar V, Nagy P, Kittel Á, Buzás EI, Ferdinandy P, Giricz Z.
Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods.
PLoS One. 2015 Dec 21;10(12):e0145686. doi: 10.1371/journal.pone.0145686. eCollection 2015.
Rassaf T, Ferdinandy P, Schulz R.
Nitrite in Organ Protection.
Br J Pharmacol. 2014 Jan;171(1):1-11.
Csont T, Sárközy M, Sz Cs G, Sz Cs C, Bárkányi J, Bencsik P, Gáspár R, Földesi I, Csonka C, Kónya C, Ferdinandy P.
Effect of a multivitamin preparation supplemented with phytosterol on serum lipids and infarct size in rats fed with normal and high cholesterol diet.
Lipids Health Dis. 2013 Sep 25;12(1):138.
Görbe A, Varga ZV, Pálóczi J, Rungarunlert S, Klincumhom N, Pirity MK, Madonna R, Eschenhagen T, Dinnyés A, Csont T, Ferdinandy P.
Cytoprotection by the NO-Donor SNAP Against Ischemia/Reoxygenation Injury in Mouse Embryonic Stem Cell-Derived Cardiomyocytes.
Mol Biotechnol. 2014 Mar;56(3):258-64.
Csonka C, Kupai K, Bencsik P, Görbe A, Pálóczi J, Zvara A, Puskas LG, Csont T, Ferdinandy P.
Cholesterol-enriched diet inhibits cardioprotection by ATP-cholesterol-enriched diet inhibits cardioprotection by ATP-sensitive potassium channel activators cromakalim and diazoxide.
Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H405-13.
Kadomatsu K, Bencsik P, Görbe A, Csonka C, Sakamoto K, Kishida S, Ferdinandy P.
Therapeutic Potential of Midkine in Cardiovascular Diseases.
Br J Pharmacol. 2014 Feb;171(4):936-44.
Bencsik P, Pálóczi J, Kocsis GF, Pipis J, Belecz I, Varga ZV, Csonka C, Görbe A, Csont T, Ferdinandy P.
Moderate inhibition of myocardial matrix metalloproteinase-2 by ilomastat is cardioprotective.
Pharmacol Res. 2014 Feb;80:36-42.
Csonka C, Szucs G, Varga-Orvos Z, Bencsik P, Csont T, Zvara Á, Puskás LG, Ferdinandy P.
Ischemic postconditioning alters the gene expression pattern of the ischemic heart.
Exp Biol Med (Maywood). 2014 Feb;239(2):141-50.
Giricz Z, Varga ZV, Baranyai T, Sipos P, Pálóczi K, Kittel Á, Buzás EI, Ferdinandy P.
Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles.
J Mol Cell Cardiol. 2014 Mar;68:75-8.
Varga ZV, Zvara A, Faragó N, Kocsis GF, Pipicz M, Gáspár R, Bencsik P, Görbe A, Csonka C, Puskas LG, Thum T, Csont T, Ferdinandy P.
MicroRNAs associated with ischemia/reperfusion injury and cardioprotection by ischemic pre- and postconditioning: ProtectomiRs.
Am J Physiol Heart Circ Physiol. 2014 May 23.
Andreadou I, Iliodromitis EK, Rassaf T, Schulz R, Papapetropoulos A, Ferdinandy P.
The role of gasotransmitters NO, H2 S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning.
Br J Pharmacol. 2014 Jun 12.
Csonka C, Páli T, Bencsik P, Görbe A, Ferdinandy P, Csont T.
Measurement of NO in biological samples.
Br J Pharmacol. 2014 Jul 2
Madonna R, Geng YJ, Shelat H, Ferdinandy P, De Caterina R.
High glucose-induced hyperosmolarity impacts proliferation, cytoskeleton remodeling and migration of human induced pluripotent stem cells via aquaporin-1.
Biochim Biophys Acta. 2014 Nov;1842(11):2266-75.
Sárközy M, Fekete V, Szűcs G, Török S, Szűcs C, Bárkányi J, Varga ZV, Földesi I, Csonka C, Kónya C, Csont T, Ferdinandy P.
Anti-diabetic effect of a preparation of vitamins, minerals and trace elements in diabetic rats: a gender difference.
BMC Endocr Disord. 2014 Aug 26;14:72.
Ferdinandy P, Hausenloy DJ, Heusch G, Baxter GF, Schulz R.
Interaction of Risk Factors, Comorbidities, and Comedications with Ischemia/Reperfusion Injury and Cardioprotection by Preconditioning, Postconditioning, and Remote Conditioning.
Pharmacol Rev. 2014 Oct;66(4):1142-1174.
Pechánová O, Varga Z, Cebová M, Giricz Z, Pacher P, Ferdinandy P.
Cardiac Nitric Oxide Signalling in Metabolic Syndrome.
Br J Pharmacol. 2015 Mar;172(6):1415-33
Lecour S, Bøtker HE, Condorelli G, Davidson SM, Garcia-Dorado D, Engel FB, Ferdinandy P, Heusch G, Madonna R, Ovize M, Ruiz-Meana M, Schulz R, Sluijter JP, Van Laake LW, Yellon DM, Hausenloy DJ.
ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies.
Cardiovasc Res. 2014 Dec 1;104(3):399-411.
Madonna R, Ferdinandy P, De Caterina R, Willerson JT, Marian AJ.
Recent developments in cardiovascular stem cells.
Circ Res. 2014 Dec 5;115(12):e71-8
Monostori P, Kocsis GF, Okrös Z, Bencsik P, Czétényi O, Kiss Z, Gellén B, Bereczki C, Ocsovszki I, Pipis J, Pálóczi J, Sárközy M, Török S, Varga IS, Kiss I, Fodor E, Csont T, Ferdinandy P, Túri S.
Different administration schedules of darbepoetin alfa affect oxidized and reduced glutathione levels to a similar extent in 5/6 nephrectomized rats.
Clin Exp Nephrol. 2013 Aug;17(4):569-74.
Sárközy M, Zvara A, Gyémánt N, Fekete V, Kocsis GF, Pipis J, Szűcs G, Csonka C, Puskás LG, Ferdinandy P, Csont T.
Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats.
Cardiovasc Diabetol. 2013 Jan 15;12:16.
Hausenloy DJ, Erik Bøtker H, Condorelli G, Ferdinandy P, Garcia-Dorado D, Heusch G, Lecour S, van Laake LW, Madonna R, Ruiz-Meana M, Schulz R, Sluijter JP, Yellon DM, Ovize M.
Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology.
Cardiovasc Res. 2013 Apr 1;98(1):7-27.
Hill C, Würfel A, Heger J, Meyering B, Schlüter KD, Weber M, Ferdinandy P, Aronheim A, Schulz R, Euler G.
Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction.
Cardiovasc Res. 2013 Jul 1;99(1):121-8.
Madonna R, Görbe A, Ferdinandy P, De Caterina R.
Glucose Metabolism, Hyperosmotic Stress, and Reprogramming of Somatic Cells.
Mol Biotechnol. 2013 Oct;55(2):169-78.
Fekete V, Murlasits Z, Aypar E, Bencsik P, Sárközy M, Szénási G, Ferdinandy P, Csont T.
Myocardial postconditioning is lost in vascular nitrate tolerance.
J Cardiovasc Pharmacol. 2013 Sep;62(3):298-303.
Szűcs G, Murlasits Z, Török S, Kocsis GF, Pálóczi J, Görbe A, Csont T, Csonka C, Ferdinandy P.
Cardioprotection by farnesol: role of the mevalonate pathway.
Cardiovasc Drugs Ther. 2013 Aug;27(4):269-77.
Varga ZV, Kupai K, Szűcs G, Gáspár R, Pálóczi J, Faragó N, Zvara A, Puskás LG, Rázga Z, Tiszlavicz L, Bencsik P, Görbe A, Csonka C, Ferdinandy P, Csont T.
MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart.
J Mol Cell Cardiol. 2013 Sep;62:111-21.
Kocsis GF, Sárközy M, Bencsik P, Pipicz M, Varga ZV, Pálóczi J, Csonka C, Ferdinandy P, Csont T.
Preconditioning protects the heart in a prolonged uremic condition.
Am J Physiol Heart Circ Physiol. 303(10):H1229-36 (2012)
Görbe A, Varga ZV, Kupai K, Bencsik P, Kocsis GF, Csont T, Boengler K, Schulz
R, Ferdinandy P.
Cholesterol diet leads to attenuation of ischemic preconditioning-induced cardiac protection: the role of connexin 43.
Am J Physiol Heart Circ Physiol. 300:H1907-13 (2011)
Szucs G, Bester DJ, Kupai K, Csont T, Csonka C, Esterhuyse AJ, Ferdinandy P, Van Rooyen J.
Dietary red palm oil supplementation decreases infarct size in cholesterol fed rats.
Lipids Health Dis. 10:103 (2011)
Csont T, Görbe A, Bereczki E, Szunyog A, Aypar E, Tóth ME, Varga ZV, Csonka C, Fülöp F, Sántha M, Ferdinandy P.
Biglycan protects cardiomyocytes against hypoxia/reoxygenation injury: Role of nitric oxide.
J Mol Cell Cardiol. 48:649-652 (2010)
Kupai K, Szucs G, Cseh S, Hajdu I, Csonka C, Csont T, Ferdinandy P.
Matrix metalloproteinase activity assays: Importance of zymography.
J Pharmacol Toxicol Methods. 61:205-209 (2010)
Csonka C, Kupai K, Kocsis GF, Novák G, Fekete V, Bencsik P, Csont T, Ferdinandy P.
Measurement of myocardial infarct size in preclinical studies.
J Pharmacol Toxicol Methods. 61:163-170 (2010)
Gorbe A, Giricz Z, Szunyog A, Csont T, Burley DS, Baxter GF, Ferdinandy P.
Role of cGMP-PKG signaling in the protection of neonatal rat cardiac myocytes subjected to simulated ischemia/reoxygenation.
Basic Res Cardiol. 105:643-650 (2010).
Ovize M, Baxter GF, Di Lisa F, Ferdinandy P, Garcia-Dorado D, Hausenloy DJ, Heusch G, Vinten-Johansen J, Yellon DM, Schulz R.
Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology.
Cardiovasc Res. 87:406-423 (2010).
Dormán G, Cseh S, Hajdú I, Barna L, Kónya D, Kupai K, Kovács L, Ferdinandy P.
Matrix metalloproteinase inhibitors: a critical appraisal of design principles and proposed therapeutic utility.
Drugs. 70:949-964 (2010)
Bencsik P, Kupai K, Giricz Z, Görbe A, Pipis J, Murlasits Z, Kocsis GF, Varga-Orvos Z, Puskás LG, Csonka C, Csont T, Ferdinandy P.
Role of iNOS and peroxynitrite-matrix metalloproteinase-2 signaling in myocardial late preconditioning in rats.
Am J Physiol Heart Circ Physiol. 299:H512-518 (2010)
Kupai K, Csonka C, Fekete V, Odendaal L, van Rooyen J, Marais de W, Csont T, Ferdinandy P.
Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite.
Am J Physiol Heart Circ Physiol. 297:H1729-35 (2009)
Kocsis GF, Pipis J, Fekete V, Kovacs-Simon A, Odendaal L, Molnar E, Giricz Z, Janaky T, van Rooyen J, Csont T, Ferdinandy P.
Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts.
Am J Physiol Heart Circ Physiol 294:H2406-2409 (2008)
Csont T, Ferdinandy P.
Letter regarding article „Biglycan is required for adaptive remodeling after myocardial infarction”.
Circulation 118:e521 (2008)
Bereczki E, Gonda S, Csont T, Korpos E, Zvara A, Ferdinandy P, Santha M.
Overexpression of biglycan in the heart of transgenic mice: an antibody microarray study.
J Proteome Res. 6:854-861(2007)
Papp A, Szommer T, Barna L, Gyimesi G, Ferdinandy P, Spadoni C, Darvas F, Fujita T, Ürge L, Dormán G.
Enhanced hit-to-lead process using bioanalogous lead evolution and chemogenomics: application in designing selective matrix metalloprotease inhibitors.
Expert Opin Drug Discov 2:707-723 (2007)
Csont T, Bereczki E, Bencsik P, Fodor G, Gorbe A, Zvara A, Csonka C, Puskas LG, Santha M, Ferdinandy P.
Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice.
Cardiovasc Res. 76:100-109 (2007)
Dormán G, Kocsis-Szommer K, Spadoni C, Ferdinandy P.
MMP inhibitors in cardiac diseases: an update.
Recent Patents Cardiovasc Drug Discov 2:186-194 (2007)
Ferdinandy P, Schulz R, Baxter GF.
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning and postconditioning.
Pharmacol Rev 59:418-458 (2007)
Giricz Z, Lalu MM, Csonka C, Bencsik P, Schulz R, Ferdinandy P.
Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition.
J Pharmacol Exp Ther 316:154-61(2006)
Konya C, Ferdinandy P.
Vitamin C: new role of the old vitamin in the cardiovascular system.
Br J Pharmacol 147:125-127 (2006)
Turan N, Csonka C, Csont T, Giricz Z, Fodor G, Bencsik P, Gyongyosi M, Cakici I, Ferdinandy P.
The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts.
Cardiovasc Res 70:384-390 (2006)
Ferdinandy P.
Peroxynitrite: just an oxidative/nitrosative stressor or a physiological regulator as well?
Br J Pharmacol 148:1-3 (2006)